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Clinical Trials/NCT03432611
NCT03432611
Unknown
Not Applicable

Evaluation of a Smartphone Application for Self Care for Women With Menstrual Pain (Primary Dysmenorrhea): a Randomized Trial

Charite University, Berlin, Germany1 site in 1 country594 target enrollmentFebruary 19, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Primary Dysmenorrhea
Sponsor
Charite University, Berlin, Germany
Enrollment
594
Locations
1
Primary Endpoint
Mean pain intensity on the days with pain
Last Updated
6 years ago

Overview

Brief Summary

With a randomized, pragmatic study the effectiveness of a smartphone app for menstrual pain in 18-34-year-old women with primary dysmenorrhea will be investigated.

Detailed Description

Smartphone apps may be useful to guide and support individuals in self-management strategies. Primary dysmenorrhea is a very common problem for women. With a randomized, pragmatic study the investigators aim to evaluate whether a smartphone app for women with menstrual pain is effective in reducing menstrual pain in 18-34-year-old women with primary dysmenorrhea. For this the investigators compare the complete smartphone app with two control versions of this app. The complete app provides evidence-based self-care information and instructions for self-acupressure in menstrual pain, the control intervention I includes self-care information, but no instructions for self-acupressure, and control intervention II includes instructions for self-acupressure, but no self-care information. The investigators aim to observe 594 women with primary dysmenorrhea over 12 menstruation cycles. The primary outcome is the mean pain intensity on the days with pain during the 6th menstruation after randomization using a numerical rating scale (NRS; 0=no pain; 10=strongest pain imaginable). Women are eligible when they suffer from primary dysmenorrhea, are between 18 and 34 years old, not pregnant and do not plan to be pregnant within the next 12 months.

Registry
clinicaltrials.gov
Start Date
February 19, 2018
End Date
March 2021
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Claudia M. Witt

Prof. Dr. med.

Charite University, Berlin, Germany

Eligibility Criteria

Inclusion Criteria

  • Female, aged 18-34 years
  • Dysmenorrhea, defined as self-reported menstrual cramps or pain during every menstrual cycle which started during the teenage years
  • No prior history of a gynecological disease that is known to be a reason for the dysmenorrhea
  • Not more than 5 days with menstrual pain outside the menstrual period itself
  • Menstruation within the last six weeks and a cycle length of 3 to 6 weeks
  • Moderate or severe pain, defined as a score equal to or higher than 6 on a numeric rating scale (NRS, 0 to 10) for the worst pain intensity during the last menstruation
  • Informed consent
  • Possession of an iPhone
  • Willingness and ability to input and share anonymous data through the study app
  • The willingness to see a doctor when 1) pain is getting worse than usual, 2) pain medication is not helping, and 3) when the pain is still present well before or well after the period.

Exclusion Criteria

  • Known pregnancy
  • Pregnancy already planned for the forthcoming 12 months

Outcomes

Primary Outcomes

Mean pain intensity on the days with pain

Time Frame: Daily during the 6th menstruation after randomization

The mean pain intensity on the days with pain during the 6th menstruation after randomization using a numerical rating scale (NRS; 0=no pain; 10=strongest pain imaginable).

Secondary Outcomes

  • Adverse reaction(End of menstruation (1st to 12th menstrual cycles))
  • User satisfaction(End of menstruation (1st to 12th menstrual cycles))
  • Days with pain medication(Daily during menstruation (1st to 12th menstrual cycles))
  • Responder(Daily during menstruation (1st to 12th menstrual cycles))
  • Days with absence from work, training, or studies(Baseline, end of menstruation (1st to 12th menstrual cycles))
  • Number of days with pain (duration of pain)(Daily during menstruation (1st to 12th menstrual cycles))
  • Severe adverse events(End of menstruation (3rd, 6th, 9th, and 12th menstrual cycles))
  • Frequency of acupressure application(5 days before menstruation and during menstruation (1st to 12th menstrual cycles))
  • Mean pain intensity on the days with pain(Baseline; daily during menstruation (1st to 5th and 7th to 12th menstrual cycles))

Study Sites (1)

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