Pilot study for the treatment response evaluation in glioblastoma with vessel architectural imaging (VAI)

Completed

• Conditions: brain cancer; Brain tumour; GBM; glioblastoma multiforme; 10029211

• Registration Number: NL-OMON46808
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

- Histological confirmed glioblastoma after standard treatment
- New contrast enhancing lesion on follow-up MRI
- Written informed consent

Exclusion Criteria

- Minors (<18 years)
- Subtotal resection of the tumour resulting in residual enhancement on post-operative MRI
- History of previous new enhancing lesion on follow-up MRI
- Treatment different than standard treatment
- Contraindication for MRI (ferromagnetic material in body, pregnancy, claustrophobia)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary endpoints are true positive, false positive, true negative, and false<br /><br>negative values of VAI MRI. The reference will be definitive diagnosis<br /><br>according to standard radiological follow-up. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>