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临床试验/CTRI/2025/08/092629
CTRI/2025/08/092629尚未招募不适用

l Comparison Of Ultrasound -Guided Internal Jugular Vein And Supraclavicular Subclavian Vein -A Randomized Control Trial

Josemine Davis1 个研究点 分布在 1 个国家目标入组 160 人开始时间: 2025年8月28日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
160
试验地点
1
主要终点
First attempt success rate and immediate complication such as hematoma , carotid artery puncture , pneumothorax.

研究概览

简要总结

Central venous cannulation (CVC) is a vital intervention in the operation theatre, intensive

care unit, and emergency room. Common clinical applications of CVC include central

venous pressure (CVP) monitoring in major surgeries, administration of drugs,

hyperosmolar solutions and blood products.

Internal jugular vein (IJV) cannulation being the most adopted route for central venous

access, it is associated with several problems like proximity to neck vessels leading to

arterial puncture, and difficulty in access in obese, edematous, and hypovolemic patients.

The subclavian vein is advantageous anatomically owing to its huge caliber, absence of

valves, and support of surrounding structures which keeps the vein patent even in shock.

Traditionally, the internal jugular vein (IJV) and subclavian vein have been the preferred sites

for central venous access.

With advances in technology, the use of ultrasound has become the standard of care in

medical practice overcoming the limitations of landmark-based techniques. Ultrasound allows

realtime visualization of the vein ensuring successful cannulation with fewer attempts and

less complication rate.However, the choice between these two approaches remains a

subject of clinical debate, especially with the advent of ultrasound guidance, which has

significantly improved the accuracy and safety of these procedures.

As anesthesiologist Tomasz Czarnik and co-authors (2009) say: “In conclusion, subclavian

venous cannulation via the supraclavicular approach is an excellent method of central venous

access in anesthesia. The procedure success rate and the significant complication rate are

comparable to other techniques of central venous cannulation especially to jugular access,

which is regarded by most physicians as the safest one. Mechanical ventilation is not a risk

factor associated with significant complications. The supraclavicular approach should be

considered, especially in neuroanesthesia, where the right jugular approach could be

associated with cerebral perfusion pressure reduction, intracranial pressure elevation, and

venous stasis. The supraclavicular approach seems to be more comfortable than the jugular

approach in a conscious patient. This method can be successfully and relatively safely used

as a primary or alternative technique when other catheterization sites are not available to

augment the spectrum of catheterization possibilities, even in mechanically ventilated

patients”.

This thesis aims to compare the efficacy, safety, and clinical outcomes of ultrasound-guided

internal jugular vein and supraclavicular subclavian vein cannulation.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • All adult patients from 18years to 80 years , undergoing all major elective surgeries .And patients who are able to provide consent are included in the study.

排除标准

  • Prior ipsilateral venous cannulation will not be included in the study.
  • Any contraindication to ultrasound guidance .
  • Pregnant patient not included in the study and patient on anticoagulation therapy also not included in the study.

结局指标

主要结局

First attempt success rate and immediate complication such as hematoma , carotid artery puncture , pneumothorax.

时间窗: 20 minutes

次要结局

  • Time of insertion & operator satisfaction.(10 minutes)

研究者

发起方
Josemine Davis
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Sumit Chikara

Army Hospital Research and Referral

研究点 (1)

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