To determine the efficacy between time dependent vs volume dependent chest tube drainage removal protocol following talc slurry pleurodesis in malignant pleural effusion - A randomized control trial
Phase 1
Not yet recruiting
- Conditions
- Health Condition 1: C00-D49- Neoplasms
- Registration Number
- CTRI/2020/07/026652
- Lead Sponsor
- Christian Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age more than 18 years with biopsy/cytology proven malignant pleural effusion and planned for TALC pleurodesis
Exclusion Criteria
1.Patients who do not give informed consent
2.Expected survival period of less than 2 months
3.Patient with earlier pleurodesis failure
4.Evidence of trapped lung following drainage of pleural fluid- Trapped lung defined as evidence of failed re-expansion of the lung after pleural fluid drainage and confirmed by chest X-ray
5.Ipsilateral endobronchial obstruction
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Efficacy of Pleurodesis in two different chest drain removal protocols (volume versus time based chest drain removal protocols)Timepoint: Sucess of pleurodesis will be assessed at the end of 7days, 1month and 3 months.
- Secondary Outcome Measures
Name Time Method To compare complications and Mortality in two arms <br/ ><br>Timepoint: Complications and mortailty will be assessed at the end of 7days, 1month and 3 months.;To compare the duration of hospital stay in two arms following talc pleurodesisTimepoint: Will be assessed only once at the end of hospital stay