Anti-nucleosome B Lymphocytes in Lupus

Terminated

• Conditions: Systemic Lupus Erythematosus With or Without Clinical Activity
• Interventions: Other: Venous blood sampling

• Registration Number: NCT01889654
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

Lupus disease is characterized by the production of pathogenic autoantibodies, which participate in end-organ damages. The phenotype of B cells producing the pathogenic autoantibodies in lupus patients is today unknown. Antinucleosome antibodies are characteristic of lupus disease.This project proposes to detect antinucleosome B cells in lupus patients and to analyse their phenotype and their frequency.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-06-25
• Study First Submitted QC: 2013-06-27
• Study First Posted: 2013-06-28
• Study Start: 2014-02
• Primary Completion: 2015-07
• Study Completion: 2015-07
• Status Verified: 2017-01
• Last Update Submitted: 2017-09-07
• Last Update Posted: 2017-09-11

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 4

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
patient	Venous blood sampling	-
healthy volunteers	Venous blood sampling	-

Primary Outcome Measures

Name	Time	Method
all cause mortality	1 year

Trial Locations

Locations (1)

Les Hôpitaux Universitaires de Strasbourg; 🇫🇷 Strasbourg, Bas Rhin, France