Safety and Efficacy of Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement
- Conditions
- Liver Diseases
- Interventions
- Procedure: Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement
- Registration Number
- NCT06336850
- Lead Sponsor
- Methodist Health System
- Brief Summary
The purpose of this study is to evaluate the efficacy, safety, and adequacy of Endoscopic Ultrasound (EUS) Portal Pressure Gradient Measurement (PPGM) in patients undergoing EUS-guided liver biopsies.
- Detailed Description
Patients undergoing EUS-guided liver biopsy may qualify to participate in this study. The purpose of this study is to evaluate the efficacy, safety, and adequacy of EUS- Portal Pressure Gradient Measurement (PPGM) in patients with liver disease referred for EUS-guided liver biopsy.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Treatment Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement Patients undergoing Endoscopic-Ultrasound Guided liver biopsies and Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurements
- Primary Outcome Measures
Name Time Method Portal Pressure Gradient Measurements from Hepatic and Portal Veins 2 years A catheter is inserted into the hepatic vein before hepatic venous pressure and portal vein pressure are recorded
- Secondary Outcome Measures
Name Time Method Correlation between Portal Pressure Gradient Measurements and the presence or absence of portal hypertension 2 years Statistical tests to determine relationship between portal pressure gradient measurements and portal hypertension
Clinical significance between portal pressure gradient measurement and portal hypertension 2 years Presence of varices, hypertensive gastropathy, or thrombocytopenia.
Trial Locations
- Locations (1)
Methodist Dallas Medical Center
🇺🇸Dallas, Texas, United States