跳至主要内容
临床试验/NCT06445660
NCT06445660招募中不适用

The Feasibility of a Radiological Score Based on Quantified Analysis of Computed Tomography Signs for Recognizing Salvageable Bowel in Acute Mesenteric Ischemia: A Retrospective Analysis of Prospective Study

University of Tartu1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2022年6月6日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
200
试验地点
1
主要终点
Frequency rate

研究概览

简要总结

Computed tomography (CT) is the standard modality for scanning patients with critical acute abdominal conditions, including suspected acute mesenteric ischemia (AMI). CT imaging can potentially differentiate between reversible and irreversible ischaemic damage of the bowel. This moment is pivotal in selecting the treatment strategy for AMI - in the absence of irreversible damage; reperfusion therapy can preserve intestinal viability, thereby avoiding the need for bowel resection. The present study tests the hypothesis that combining several symptoms may enhance the diagnostic performance of CT scanning in detecting salvageable bowel in patients with AMI. This study is an ancillary component of the AMESI study (Clinical Trials: NCT05218863) - a prospective, multicentre observational study aimed at identifying the incidence and describing the outcomes of acute mesenteric ischemia (AMI) in adult hospitalized patients. The ultimate purpose of the present study is to create a computed tomography-based radiological score for the assessment of bowel viability in patients with AMI.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Participant in AMESI study
  • confirmed or suspected acute mesenteric ischaemia
  • CT scan of the entire abdominal cavity / full body using intravenous contrast media is available

排除标准

  • Scans without the use of an intravenous contrast media or those covering only a partial area of the abdomen will be excluded.

结局指标

主要结局

Frequency rate

时间窗: up to one month

Frequency rate of common radiological signs in AMI patients with and without salvageable bowel.

次要结局

  • Performance of the radiological score(up to one month)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Annika Reintam Blaser

associate professor

University of Tartu

研究点 (1)

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