Research for biomarkers of inflammatory bowel disease. - Investigation of the usefulness of LRG for evaluation of disease condition after adalimumab treatments
- Conditions
- Crohn's disease, ulcerative colitis
- Registration Number
- JPRN-UMIN000019958
- Lead Sponsor
- Iwate Medical University Kochi Medical School Hospital Keio University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 80
Not provided
1. Patients with history of following intestinal surgery. Patients who are scheduled for following surgery. CD : enterectomy within 12 weeks prior to enrollment pouch or stoma (except rectostomy) UC : subtotal colectomy with ileorectostomy or colectomy with ileoanal pouch, Kock pouch and ileostomy 2. Patients with history of adalimumab treatment 3. Patients who had not showed initial response to infliximab before and patients with secondary failure to infliximab 10 mg/kg 4. Patients with serious infections 5. Patients with active tuberculosis 6. Patients with a history of hypersensitivity toadalimumab 7. Patients with demyelinating disease (Multiple sclerosis, etc) or with history of demyelinating disease 8. Patients with congestive heart failure 9. Patients who is determined inappropriate to participate to this study by the investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method