Evaluation of the Dose Received by the Prostate With in Vivo Dosimetry in Patients Treated With Daily IGRT Associated With IMRT Using Two Repositioning Techniques for Localized Prostate Cancer
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Enrollment
- 3
- Locations
- 1
- Primary Endpoint
- dosimetry (measurement of the absorbed dose, delivered to prostate, by ionizing radiation)
Study Overview
Brief Summary
This study evaluates the dose received by the prostate with in vivo dosimetry when delivering image guided radiation therapy (IGRT) associated with intensity modulated radiation therapy (IMRT) for patients with localized prostate cancer using two repositioning techniques: fiduciary markers or soft tissues.
Detailed Description
10 participants will receive a cone beam computed tomography (CBCT) repositioning, while the other 10 will receive a kV imaging of fiducial marker repositioning. The principal objective is to evaluate and compare the dose received by the prostate using two repositioning techniques.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Health Services Research
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •male > 18 years
- •carcinoma of the prostate histologically confirmed
- •localized stage
- •favorable, intermediate and unfavorable groups according to NCCN or D'Amico classification
- •patients must have signed a written informed consent form
- •patients must be affiliated to a Social Health Insurance.
Exclusion Criteria
- •metastasis
- •indication for pelvic radiation
- •anticoagulant therapy
- •lateral or bilateral hip replacement
- •patient receiving an adult protective services
- •Patient unable to comply with the required medical follow-up for geographic, social or psychological reasons
Arms & Interventions
CBCT
cone beam computed tomography (CBCT) repositioning
Intervention: CBCT (Other)
CBCT
cone beam computed tomography (CBCT) repositioning
Intervention: IGRT Associated With IMRT (Radiation)
fiducial markers
kV imaging of fiducial marker repositioning
Intervention: fiducial marker (kV imaging) (Other)
fiducial markers
kV imaging of fiducial marker repositioning
Intervention: IGRT Associated With IMRT (Radiation)
Outcomes
Primary Outcomes
dosimetry (measurement of the absorbed dose, delivered to prostate, by ionizing radiation)
Time Frame: 8 weeks
Secondary Outcomes
No secondary outcomes reported