Comparison of Antinociceptive Effects of Ketamine and Magnesium Used for Sedation in Hysteroscopy Cases
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Antinociceptive effects of ketamine and magnesium
研究概览
简要总结
This study aims to compare the antinociceptive effects of ketamine and magnesium used in addition to midazolam, fentanyl, propofol and remifentanil agents preferred in hysteroscopy cases. It is conducted to observe the effect of ketamine and magnesium use on total additional propofol doses and additional remifentanil doses.
详细描述
Sedation is generally preferred in hysteroscopy cases. The most commonly used intravenous drugs are midazolam, fentanyl, propofol and remifentanil. Multimodal analgesia, which is intended to be provided in hysteroscopy cases, is a strategy that includes the use of two or more analgesic agents and techniques to provide adequate analgesia; and aims to minimize side effects such as bradycardia, hypotension, respiratory depression, pruritus, and postoperative nausea and vomiting. Multimodal analgesia improves patient and surgical comfort by applying additional drugs to existing agents, reduces postoperative complications, and thus helps to shorten hospital stays and reduce costs. Whether magnesium contributes to this multimodal analgesia will be investigated observationally, based on its antinociceptive effects.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 55 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •ASA I-II patients
- •Patients aged 18-55
- •Patients undergoing hysteroscopy
排除标准
- •Patients who develop surgical complications during hysteroscopy
- •Patients with cardiovascular failure (ejection fraction <40%, patients with atrioventricular conduction disorder
- •Patients with history of cerebrovascular disease
- •Liver dysfunction (transaminases above normal level), Renal failure (creatine > 150 μmol/L),
- •Preoperative opioid use
- •History of neuromuscular disease
- •History of drug or alcohol abuse
- •Patients who develop the need for endotracheal intubation
结局指标
主要结局
Antinociceptive effects of ketamine and magnesium
时间窗: During the hysteroscopic procedures.
Observe the effect of ketamine and magnesium use on total additional doses of propofol and additional doses of remifentanil.
次要结局
未报告次要终点
研究者
SULEYMAN SARI
Attending Physician
Ankara Etlik City Hospital
