NCT01719068Unknown不适用
Early Detection of Lung Cancer and Mesothelioma in Workers Exposed to Asbestos
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Development of Model to Predict Workers at highest risk of lung cancer/mesothelioma
研究概览
简要总结
This is a pilot study that aims to develop a lung cancer screening program for workers in British Columbia, Canada exposed to asbestos who are at risk of developing lung cancer/pleural mesothelioma. This is high risk population is at of respiratory system diseases as a result of their occupational exposures. Additionally, knowledge garnered from this study will allow us to develop other studies that will further our understanding of asbestos related lung cancer and mesothelioma.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Women or men age 50 to 79 years
- •history of exposure to asbestos at work and one or more of the following:
- •lung cancer risk ≥2% over 3 years or
- •asbestosis or pleural plaques on a chest x-ray or
- •abnormal auto-antibodies level using the EarlyCDT test
- •Capable of providing informed consent for screening procedures (low dose spiral CT, lung function, blood biomarkers).
排除标准
- •Any medical condition, such as severe heart disease (e.g. unstable angina, chronic congestive heart failure), acute or chronic respiratory failure, or any disorder, that in the opinion of the physician unlikely to benefit from screening due to shortened life-expectancy from co-existing illnesses
- •Have been previously diagnosed with mesothelioma
- •Have had other cancer within the past 5 years with the exception of the following cancers: non-melanomatous skin cancer,localized prostate cancer, carcinoma in situ (CIS) of the cervix, or superficial bladder cancer. Treatment of the exceptions must have ended >6 months before registration into this study
- •Pregnancy
- •Unwilling to have a low dose CT scan of chest
- •Unwilling to sign a consent
结局指标
主要结局
Development of Model to Predict Workers at highest risk of lung cancer/mesothelioma
时间窗: 3 years
次要结局
未报告次要终点
研究者
研究点 (1)
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