NCT04160208招募中不适用
DNA Damage and Subfertility in Males - Impact on Assisted Reproductive Treatment Outcome
Regionshospitalet Viborg, Skive1 个研究点 分布在 1 个国家目标入组 1,350 人开始时间: 2019年10月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,350
- 试验地点
- 1
- 主要终点
- Number of particpants achieving live birth
研究概览
简要总结
A obvational prospective cohort study of men undergoing IUI, IVF and ICSI treatment in Denmark. The aim is to asses the impact of sperm DNA damage, measured as DNA fragmentation index (DFI), on reproductive outcomes after assisted reproductive technology (ART).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •First cycle treatment
排除标准
- •TESA/PESA, more than one cycle
结局指标
主要结局
Number of particpants achieving live birth
时间窗: week 23-42 of pregnancy
Birth of a living child after week 23. Registered through self-reported schemes sent to the clinic.
次要结局
- Number of participants with clinical pregnancy(week 7-8 of pregnancy)
- Number of participants with biochemical pregnancy(Day 14-17 of pregnancy)
- Cumulative live birth rate(9-24 months after inclusion)
研究者
Peter Humaidan
Professor
Regionshospitalet Viborg, Skive
研究点 (1)
Loading locations...
相似试验
招募中
不适用
DNA Damage and Subfertility in Males - Lifestyle Interventions to Improve Male Fertility and HealthInfertilityNCT04183374Regionshospitalet Viborg, Skive680
已完成
不适用
Impact of Antioxidant Treatment on DNA Fragmentation IndexMale InfertilityNCT03466229Region Skane79
招募中
不适用
Oxidative Stress and Male Infertility.Male InfertilityNCT06210568IRCCS San Raffaele800
已完成
2 期
FSH Receptor Polymorphism p.N680S and Efficacy of FSH TherapyMale InfertilityNCT02349945Azienda USL Modena88
招募中
不适用
Single and Double DNA Strand Breaks in Males With Unexplained Infertility Attending Fertility TreatmentInfertility, MaleNCT05846256Peter Humaidan125