Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Caudal Epidural Block
- Conditions
- İnguinal Hernia
- Interventions
- Registration Number
- NCT07056244
- Lead Sponsor
- Sohag University
- Brief Summary
The goal of This prospective, randomized, double-blind comparative study is to compare the efficacy of dexamethasone and dexmedetomidine as adjuvants to bupivacaine 0.125% in caudal epidural block for pediatrics undergoing inguinal hernia surgery, aged 2-6 years.
of Both sex.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 80
- Children aged 2-6 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status I and II.
- Scheduled for inguinal hernia surgery
- Parents or legal guardians refusal.
- Known hypersensitivity to any study drugs.
- Abnormal sacral anatomy
- Local infection at the injection site.
- Neurological disease.
- Coagulopathy.
- Mental retardation.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description group A will receive Bupivacaine + Dexmedetomidine Dexmedetomidine Patients will receive Bupivacaine 0.125% at 0.5 ml/kg + Dexmedetomidine 1.5 mcg/kg for post operative analgesia. group B will receive Bupivacaine + Dexamethasone Dexamethasone Patients will receive Bupivacaine 0.125% at 0.5 ml/kg + Dexamethasone 0.2 mg/kg for post operative analgesia.
- Primary Outcome Measures
Name Time Method duration of postoperative analgesia "Pain scores will be assessed at 15-minute intervals during the first two hours postoperatively, then at 4, 6, 8,12 and 24 hour" FLACC scale (Face, Leg, Activity, Crying, Consolability) total score of 0-10 ,so the duration of analgesia will be defined as the time from caudal injection to the point when FLACC score exceeds 4.
- Secondary Outcome Measures
Name Time Method Pain score "Pain scores will be assessed at 15-minute intervals during the first two hours postoperatively, then at 4, 6, 8,12 and 24 hour" Postoperative pain will be evaluated using the FLACC scale (Face, Leg, Activity, Crying, Consolability). Pain scores will be assessed at 15-minute intervals during the first two hours postoperatively, then at 4, 6, 8,12 and 24 hour. The duration of analgesia will be defined as the time from caudal injection to the point when FLACC score exceeds 4, at which time rescue analgesia is needed
Trial Locations
- Locations (1)
Sohag university Hospital
🇪🇬Sohag, Egypt
Sohag university Hospital🇪🇬Sohag, EgyptMagdy M Amin, professorContact