NCT01154608已完成不适用
Effect of Enzyme Therapy on Protein Metabolism in Chronic Pancreatitis
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement1 个研究点 分布在 1 个国家目标入组 11 人开始时间: 2005年4月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- transfer of dietary nitrogen to metabolic pools
研究概览
简要总结
Pancreatic exocrine insufficiency is known to impair nutrient absorption, especially fat, but few data exist about protein absorption. We aimed to investigate this question and assess the enzyme substitution efficiency using a sensitive method.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Chronic pancreatitis
- •Pancreatic insufficiency
- •Enzyme therapy treatment
排除标准
- •Hepatic failure
- •Pregnancy
- •Positive serology to HIV, HCV, AGHbS, gastro-intestinal disease
研究组 & 干预措施
pancreatic enzymes
Experimental
干预措施: Creon (Drug)
control
Placebo Comparator
干预措施: No enzyme therapy (Other)
结局指标
主要结局
transfer of dietary nitrogen to metabolic pools
次要结局
未报告次要终点
研究者
研究点 (1)
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