NCT06357923招募中不适用
Study of the Evolution of the Expression of the LAMP-2 Protein During the Advance as Well as Variations and Allelic Mutations in the Main Genes Involved in the Occurrence of Age-related Myelodysplastic Syndromes
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Expression level of LAMP2 (protein and isoform A and B mRNA)
研究概览
简要总结
Recruitment on the RAV pole in consultation or day hospital. Competitive recruitment of subjects > 60 years of age respecting a male/female ratio = 1.
详细描述
Recruitment on the RAV pole in consultation or day hospital. Competitive recruitment of subjects > 60 years of age respecting a male/female ratio = 1. After explanations and collection consent, collection of the patient's socio-demographic and medical characteristics and then carrying out a Peripheral venous blood sample (2 x 5ml tubes).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women over 60 years of age.
排除标准
- •Inability to Understand Consent,
- •Non-Security Beneficiaries
- •social, subjects protected by law, subjects deprived of liberty,
- •history of breast cancer,
- •brain tumor,
- •melanoma,
- •colon cancer,
- •lung cancer,
- •prostate cancer,
- •lymphoma,
- •syndrome myelodysplastic/myeloproliferative,
- •leukemia,
- •history of radiation therapy.
研究组 & 干预措施
evaluation of LAMP-2 protein expression
Other
dosing of level expression of LAMP-2
干预措施: dosage (Diagnostic Test)
结局指标
主要结局
Expression level of LAMP2 (protein and isoform A and B mRNA)
时间窗: day 0
dosage
次要结局
- Presence of mutation in the "Oncomin Myeloid Reasearch Assay" gene panel targeting approximately 40 Different genes(day 0)
研究者
研究点 (1)
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