NL-OMON36731Not yet recruitingNot Applicable
Pilot study to investigate whether oral phosphorus binders can reduce FGF23 levels and can influence vascular function as measured by pulse wave velocity in patiens with chronic kidney disease stage 3 (eGFR 30-60 ml/min/1,73 m2). - Effect van fosfaat verlaging op FGF23 en bloedvaten
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 20
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •1.patients with eGFR 30-60 ml/min/1,73 m2
- •2.serum phosphorus level <1,49 mmol/L and >0,9 mmol/L
- •3.age >18 year
- •4.informed consent
Exclusion Criteria
- •1. known allergy or intolerance for sevelamer-containing drugs
- •2. patients with heart failure
- •3. Use of phosphate binder therapy
- •4. Patients dependent on tube-feeding or those with malabsorption syndrome
- •5. rapidly deteriorating renal function
- •6. pregnant woman
- •7 patient with kidney transplantation
Investigators
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