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Deep Breathing Techniques (Pranayama) in Pregnancy

Not Applicable
Completed
Conditions
Blood Pressure
Hypertension in Pregnancy
Pregnancy Related
Interventions
Behavioral: Alternate Nostril Breathing
Behavioral: Bhramari Breathing
Behavioral: Sheetali Breathing
Registration Number
NCT05341921
Lead Sponsor
Children's Mercy Hospital Kansas City
Brief Summary

Slow deep breathing actives the vagal nerve and leads to a natural reduction in physiological parameters such as blood pressure, heart rate and digestion. The effects of these techniques have not been assessed in pregnancy. The primary objective is to assess the effects of various yogic deep breathing techniques on blood pressure during pregnancy. The breathing exercises will include Alternate nostril breathing, Bhramari breathing, and Sheetali breathing. A secondary objective will be to assess the effects of these breathing exercises on other physiological parameters including heart rate, heart rate variability, body temperature, cardiac output, vascular resistance and respiratory rate.

Detailed Description

The trial will be conducted as a pilot study in one study visit, which will be conducted in two phases. Phase I will be conducted on normotensive pregnant women and Phase II will be conducted on hypertensive pregnant women. Participants will be in their third trimester of pregnancy (28 weeks onwards).

Upon presentation, they will be randomized into one of three groups: Alternate nostril breathing, Bhramari breathing or Sheetali breathing. Maternal monitoring devices will be placed on the patient before the intervention. The fetus will be monitored by external monitors consisting of a fetal heart rate monitor and tocodynamometer to assess uterine activity. Fetal position will be assessed before and after the intervention by ultrasound. All devices will obtain a reading for 15 minutes before, during and after the intervention.

Intervention: In an upright, seated position, the participant will engage in a total of 15 minutes of one deep breathing technique. The breathing practice will be conducted in three, 5-minute increments with a one-minute break between each session. These breathing techniques are easy to learn and participants will be taught how to perform the exercise (visual demonstration, verbal and written instructions will be provided). Participants will be given the opportunity to practice the breathing technique and ask any questions prior to initiating monitoring.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
62
Inclusion Criteria
  • Any pregnant woman in the 3rd trimester after 28 weeks of pregnancy who is/has
  • 18 years of age or older
  • English speaking
  • Phase II Only- Chronic hypertension - defined as pre-existing elevated blood pressure prior to pregnancy or less than 20 weeks gestation (Systolic blood pressure greater than or equal to 140 mmHg and /or a diastolic blood pressure greater than or equal to 90 mmHg) with or without antihypertensive use
  • Phase II Only- Gestational hypertension - defined as elevated blood pressure (Systolic blood pressure greater than or equal to 140 mmHg and /or a diastolic blood pressure greater than or equal to 90 mmHg) after 20 weeks of pregnancy without any evidence of end-organ damage or proteinuria, with or without antihypertensive use
  • Phase II Only- Preeclampsia without severe features - defined as elevated blood pressure (Systolic blood pressure greater than or equal to 140 mmHg but less than 160 mmHG and /or a diastolic blood pressure greater than or equal to 90 mmHg but less than 110 mmHg on two or more occasions 4 hours or more apart) with evidence of proteinuria, with or without antihypertensive use
Exclusion Criteria
  • Any unstable maternal or fetal condition that requires urgent delivery
  • Any concerns for pre-eclampsia with or without severe features (i.e. Development of HELLP syndrome or eclampsia)
  • Severe pulmonary disease
  • Active or acute pulmonary disease
  • Known deviated nasal septum
  • Does not desire to perform breath-controlled exercises
  • Low blood pressure defined as baseline blood pressure less or equal to a systolic of 90 mmHg and/or a diastolic blood pressure of 60 mmHg
  • Cannot roll their tongue
  • Have difficulty or cannot breathe through their nose

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Alternate Nostril Breathing Phase IAlternate Nostril BreathingAlternate nostril breathing for normotensive women in 3rd trimester of pregnancy
Bhramari Breathing Phase IBhramari BreathingBhramari breathing for normotensive women in 3rd trimester of pregnancy
Sheetali Breathing Phase IISheetali BreathingSheetali breathing for hypertensive women in 3rd trimester of pregnancy
Alternate Nostril Breathing Phase IIAlternate Nostril BreathingAlternate nostril breathing for hypertensive women in 3rd trimester of pregnancy
Sheetali Breathing Phase ISheetali BreathingSheetali breathing for normotensive women in 3rd trimester of pregnancy
Bhramari Breathing Phase IIBhramari BreathingBhramari breathing for hypertensive women in 3rd trimester of pregnancy
Primary Outcome Measures
NameTimeMethod
Change of blood pressure from baseline in normotensive and hypertensive women in 3rd trimester pregnancy while utilizing various pranayama breathing techniquesOne visit, 15 minute intervention

Continuous blood pressure monitored while participants engage in a deep breathing technique (pranayama breathing)

Secondary Outcome Measures
NameTimeMethod
Change of heart rate from baseline to after the interventionOne visit, 15 minute intervention

Continuous heart rate monitor will be applied

Change in body temperature from baseline to after the interventionOne visit, 15 minute intervention

Continuous temperature monitor will be applied

Change in cardiac output from baseline to after the interventionOne visit, 15 minute intervention

Continuous cardiac output monitor will be applied

Trial Locations

Locations (1)

Advent Health Shawnee Mission Birth Center

🇺🇸

Merriam, Kansas, United States

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