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Clinical Trials/NCT06539312
NCT06539312
Recruiting
Not Applicable

Project ASTHMA - Aligning With Schools To Help Manage Asthma and Decrease Health Inequities

State University of New York at Buffalo1 site in 1 country400 target enrollmentSeptember 27, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Asthma in Children
Sponsor
State University of New York at Buffalo
Enrollment
400
Locations
1
Primary Endpoint
Asthma exacerbations
Status
Recruiting
Last Updated
3 months ago

Overview

Brief Summary

Children with asthma from communities that experience health inequities frequently do not receive guideline-based asthma care, and as a result, account for a disproportionate percentage of asthma exacerbations, emergency department visits, and hospitalizations. Project ASTHMA (Aligning with Schools To Help Manage Asthma) tests the effectiveness of school-based health centers as a delivery model to improve health outcomes by providing children with guideline-based asthma assessments and preventive medication management, directly observed therapy of their preventive medication to support adherence, and self-management support. If successful, this multicomponent intervention will represent a cost effective and sustainable model to reduce asthma morbidity in historically marginalized communities, and has the potential to impact communities throughout the United States where over 2,500 school-based health centers operate.

Registry
clinicaltrials.gov
Start Date
September 27, 2024
End Date
April 30, 2028
Last Updated
3 months ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Lucy Holmes, MD

Clinical Associate Professor of Pediatrics

State University of New York at Buffalo

Eligibility Criteria

Inclusion Criteria

  • uncontrolled asthma

Exclusion Criteria

  • other chronic lung disease such as cystic fibrosis

Outcomes

Primary Outcomes

Asthma exacerbations

Time Frame: from 1 month after enrollment to the end of the school year for 1 school year; to be assessed after the end of the school year.

Number of asthma exacerbations requiring systemic steroids based on medical records

Secondary Outcomes

  • Spirometry - FEV1(to be assessed at baseline and 1-, 3-, 5- and 7-months after enrollment for 1 school year)
  • ED visits(from 1 month after enrollment to the end of the school year for 1 school year; to be assessed after the end of the school year.)
  • Quality of Life - caregiver(to be assessed at baseline and at 7-month follow-up for 1 school year)
  • Daytime asthma symptoms(to be assessed at baseline and 1-, 3-, 5- and 7-months after enrollment for 1 school year)
  • Spirometry - FEV1/FVC ratio(to be assessed at baseline and 1-, 3-, 5- and 7-months after enrollment for 1 school year)
  • Nighttime asthma symptoms(to be assessed at baseline and 1-, 3-, 5- and 7-months after enrollment for 1 school year)
  • Hospitalizations(from 1 month after enrollment to the end of the school year; to be assessed after the end of the school year.)
  • Activity Limitation(to be assessed at baseline and 1-, 3-, 5- and 7-months after enrollment for 1 school year)
  • Urgent care visits(from 1 month after enrollment to the end of the school year for 1 school year; to be assessed after the end of the school year.)
  • school absenteeism(from 1 month after enrollment to the end of the school year for 1 school year; to be assessed after the end of the school year.)

Study Sites (1)

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