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Effectiveness of intralipid in fertility rate in recurrent implantation failure (RIF) in frozen embryo transfer cycles

Phase 3
Recruiting
Conditions
Recurrent implantation failure.
Registration Number
IRCT20220725055555N1
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
160
Inclusion Criteria

Infertile patients with two or more implantation failures

Exclusion Criteria

Age more than42 years
BMI more than 35
Familial hyperlipidemia
Severe male factor infertility
AMH less than 1.5
Low quality embryo
Anatomical abnormality of uterus (Mullerian anomaly, sub mucosal fibroid , polyp ,hydrosalpinx ,.. )
Abnormal laboratory in liver function test, thyroid function test, prolactin, Lipid profile
Recurrent abortion history
Thrombophilia and anti phospholipid syndrome

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pregnancy. Timepoint: check of pregnancy test after two weeks from embryo transfer. Method of measurement: beta -HCG t titer.
Secondary Outcome Measures
NameTimeMethod
Clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: ultrasound and check of fetal heart rate.;Ongoing pregnancy. Timepoint: 14 weeks after embryo transfer. Method of measurement: ultrasound.
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