MedPath

Body representation and sensorimotor function as agents for brain reorganization and behavior change: from chronic pain to immobility and dementia

Phase 2
Conditions
chronic musculoskeletal pain
post-injury pain and motor dysfunction
F06.7
Mild cognitive disorder
Registration Number
DRKS00012748
Lead Sponsor
Institut für Neuropsychologie und Klinische Psychologie, Zentralinstitut für Seelische Gesundheit
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
189
Inclusion Criteria

Presence of group membership (chronic musculoskelettal pain; mild cognitive impairment; injury-induced immobilization; absence of these factors = healthy controls)

Exclusion Criteria

MRI exclusion criteria, subjects unable to consent, pregnancy, current mental disorder

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Student group: before training - after training (after 2 weeks), resp. experimental condition - control condition; sensorimotor changes (strength measurement)<br>2. Subjects with chronic musculoskelettal pain: before training - after training (after 12 weeks), resp. experimental condition - control condition; changes in pain level (multidimensional pain inventory)<br>3. Subjects with mild cognitive impairment: before training - after training (after 12 weeks), resp. experimental condition - control condition; changes in cognitive performance (Montreal Cognitive Assessment, CANTAB)<br>4. Subjects with injury-induced immobilization: experimental condition - control condition; degree of sensorimotor deficits (strength measurement, sensory thresholds; only after immobilization)
Secondary Outcome Measures
NameTimeMethod
1. Student group: before training - after training, resp. experimental condition - control condition; cortical organisation of sensorimotor brain areas (fMRI)<br>2. Subjects with chronic musculoskelettal pain: before training - after training, resp. experimental condition - control condition; quality of life (SF-36)<br>3. Subjects with mild cognitive impairment: before training - after training, resp. experimental condition - control condition; biomarkers, e.g., Tau proteins<br>4. Subjects with injury-induced immobilization: experimental condition - control condition; reconvalescence time
© Copyright 2025. All Rights Reserved by MedPath