ROX Index in Acute Respiratory Failure

• Conditions: Rox Index

• Registration Number: NCT05309239
• Lead Sponsor: Assiut University

Brief Summary

evaluation of ROX index among ICU patients to evaluate the success of non invasive ventilation or the need for intubation

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-03
• Study Start: 2022-03-21
• Study First Submitted: 2022-03-25
• Study First Submitted QC: 2022-03-25
• Last Update Submitted: 2022-03-25
• Study First Posted: 2022-04-04
• Last Update Posted: 2022-04-04
• Primary Completion: 2023-04-01
• Study Completion: 2024-03-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Participants admitted to RICU with type I and type II respiratory failure requiring NIV support with one or more of the following :

  1. PaO2/FiO2 less than or equal to 300 mmHg despite supplying oxygen at a flow rate ≥ to 10 l/min for ≥ 15 min
  2. Patients requiring ventilatory support due to increased respiratory rate ≥ 25 breaths/min or using accessory muscles of respiration

Exclusion Criteria

• 1. Absolute indication for intubation like coma, hemodynamic instability, or life-threatening arrhythmia.

  2. Contraindication to NIV like untreated pneumothorax, pneumothorax with air leak, widespread facial burn or trauma, tracheotomy,or active upper gastrointestinal bleeding.

  3. Resusal to participate in the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Success vs failure of non invasive ventilation	within 6 months	by ROX index calculation

Trial Locations

Locations (1)

Assiut university; 🇪🇬 Assiut, Egypt