Comparison of the Swallowing Functions in Sarcopenia and Dynapenia

• Conditions: Swallowing Disorder; Sarcopenia; Dysphagia

• Registration Number: NCT04960007
• Lead Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Brief Summary

The purpose of the study to investigate the comparison of the swallowing functions of the sarcopenia and dynapenia in older patients

Detailed Description

Sarcopenia is a geriatric syndrome; from skeletal muscle, and in its usefulness. Dynapenia is a picture of sarcopenia without measurable muscle mass. It has been shown that dysphagia complaints are more common in patients with sarcopenia than in the normal population, but a comparison with patients with dynapenia has not been made to the best of our knowledge. According to the algorithm of The International Society of Physical and Rehabilitation Medicine (ISPRM), experts in the special interest group on sarcopenia, in the routine examination of patients aged 60-90 years who applied to the Physical Medicine and Rehabilitation outpatient clinic with complaints of decreased muscle function, weakness, and slow movement, or "sarcopenia" or Patients with "dynapenia" and patients without Sarcopenia disease who volunteered to participate in the study will be included in the order of application to the outpatient clinic.

Study Timeline

• Study First Submitted: 2021-07-02
• Study First Submitted QC: 2021-07-02
• Study First Posted: 2021-07-13
• Study Start: 2021-07-26
• Status Verified: 2021-08
• Last Update Submitted: 2021-08-21
• Last Update Posted: 2021-08-25
• Primary Completion: 2021-08-27
• Study Completion: 2021-08-27

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 108

Inclusion Criteria

• Age between 60-90 years
• Sarcopenia and dynapenia patients in study groups
• Non- sarcopenia and non-dynapenia patients in control groups
• Patients who were accept to consent form

Exclusion Criteria

• Severe sarcopenia patients
• Cognitive limitations
• Out of age 60-90 years old
• Patients who were not accept to consent form

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The values of Pharyngeal Residue Severity	Baseline	It was assessed with Fiberoptic Endoscopic Evaluation of Swallowing. Fiberoptic Endoscopic Evaluation of Swallowing results were scored on Yale Pharyngeal Residue Severity Rating scale. The scores of scale were none, trace, mild, moderate, and severe. The high-grade symptom scores were worst, low scores were good swallowing functions.
The evaluation of eating and swallowing functions	Baseline	They were assessed by Eating Assessment Tool in participants. Composite Score ranges from 0 ( good) to 4 (worst). The minimum total score was 0 and the maximum total score was 40. The cut-off value was 3 points. High scores show worst eating and swallowing functions, and low quality of life.
The evaluation of depression	Baseline	They were assessed by Geriatric Depression Scale in participants. The scores between 0-10 were no depression, between 11-13 points were probably depression, and higher of 14 points were exact depression.
The values of muscle mass	Baseline	The diameters of tigh were measured with tailor meter by a Physical Medicine and Rehabilitation professionals (measure unit is cm).
The values of penetration and aspiration	Baseline	It was assessed with Fiberoptic Endoscopic Evaluation of Swallowing. Fiberoptic Endoscopic Evaluation of Swallowing results were scored on the Penetration and aspiration scale. The scores of scale were between 1-8 points. The high points were worst, low points were good swallowing functions.
The values of muscle strength	Baseline	They were assessed as newton by hand grip device.

Secondary Outcome Measures

Name	Time	Method
Mean of demographic	Baseline	Age, gender, history of smoke, history of morbidities, diagnosis, stage, were noted

Trial Locations

Locations (1)

Prof Dr Cemil Tascioglu City Hospital; 🇹🇷 Istanbul, Turkey