Vitamin D3 Supplementation On Level Of Blood Glucose Among Vitamin D Deficient Adult With Prediabetes.
Phase 4
- Conditions
- Health Condition 1: null- Vitamin D deficient Adult with prediabetes
- Registration Number
- CTRI/2014/12/005290
- Lead Sponsor
- A Rathiga
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 288
Inclusion Criteria
Subject who belongs to
ï?§age 30 years up to 60 years
ï?§individuals who met the diabetes risk score criteria
ï?§both male and female
ï?§fasting plasma glucose level 110 to 125 mg/dl
ï?§Oral glucose tolerance test 140 to 199mg/dl.
ï?§vitamin D3 below 30ng/dl
Exclusion Criteria
Subjects who with
diabetes under medication
currently using vitamin D supplements
hypercalcaemia above 2.65mmol/l
liver disease, Virus or autoimmune hepatitis and cirrhosis
history of hyperparathyroidism
history of arthritis
history of Pulmonary Tuberculosis
history of malabsorption
Pregnant women
History of chronic renal failure, nephrotic syndrome, Renal stone hypothyroidism, and HIV patients on antiviral drugs.
History of malignant diseases
History of inflammatory diseases
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 25 hydroxy vitamin d3 reach 50 or above 50 ng/dl <br/ ><br>Blood glucose level 80 to 100 mg/dl <br/ ><br>Timepoint: <br/ ><br>Oral supplementation of vitamin D3(Cholecalciferol) 60,000IU/week for 8 weeks followed by 60,000IU/month for 2months to achieve the serum vitamin D 50ng/dl and post test evaluation will be done on 16 th week
- Secondary Outcome Measures
Name Time Method Vitamin d 3 supplementation Effect on Insulin resistance and <br/ ><br>Effect on triglyceride <br/ ><br>Timepoint: Oral supplementation of vitamin D3(Cholecalciferol) 60,000IU/week for 8 weeks followed by 60,000IU/month for 2months to achieve the serum vitamin D 50ng/dl and post test evaluation will be done on 16 th week