NL-OMON48142
Not yet recruiting
Not Applicable
Analysis of immunological and genetic signatures in pediatric inflammatory bowel diseases - Immunological and genetic profiling in VEO-IBD (Very Early Onset)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 150
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients who are suspected of having or diagnosed with VEO\-IBD regardless of
- •race, ethnicity, and gender will be included
- •2\. Diagnosis of IBD (Crohn disease and ulcerative colitis) is based on regular
- •endoscopy, histology, intestinal MRI, video capsule endoscopy or a combination
- •of these (IBD Working Group ESPGHAN, 2014\)
- •3\. Both parents of the identified patients will be asked to participate, in
- •order to perform segregation analysis, linkage analysis, or association studies
- •4\. Written informed consent (parents and children (in case of age \>12 years)
Exclusion Criteria
- •1\. Any patient perceived by the clinical team to be at risk for complications
- •if collection of biospecimens samples for research purposes are taken (e.g.,
- •excessive bleeding)
- •2\. No fetal specimens will be taken from pregnant women for prenatal genetic
- •3\. No Approved and signed informed consent
Outcomes
Primary Outcomes
Not specified
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