NCT01418027已完成3 期
Combined Intensive and Conventional Exercise Intervention of Nonalcoholic Fatty Liver Disease
Shanghai Jiao Tong University School of Medicine1 个研究点 分布在 1 个国家目标入组 220 人开始时间: 2011年8月1日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 220
- 试验地点
- 1
- 主要终点
- Change of intrahepatic triglyceride contents
研究概览
简要总结
The prevalence of NAFLD is 50-70% in obese people. A decrease of calorie intake and increase of physical activity are recommended as an effective approach for the prevention and treatment of NAFLD. However, the exercise model for NAFLD intervention is understudied. In the present study we aim to compare the effect of intensive and conventional exercise interventions on NAFLD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects with NAFLD determined by MRS ;
- •Age 40-65 years old;
- •Waist circumference> 90cm for men and > 85cm for women.
排除标准
- 未提供
结局指标
主要结局
Change of intrahepatic triglyceride contents
时间窗: 12 months
次要结局
- Change of body weight(12 months)
- Change of waist circumference(12 months)
- Change of body fat(12 months)
- Change of abdominal fat(12 montshs)
- Change of carotid intima-media thickness(12 months)
- Change of cardiovascular risk factors (Blood pressure, lipids, glucose)(12 months)
- Change of insulin resistance(12 months)
研究者
Xiao-Ying Li
Professor
Shanghai Jiao Tong University School of Medicine
研究点 (1)
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