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The Role of Central Neck Dissection in Stage N0 Papillary Thyroid Carcinoma

Conditions
Papillary Thyroid Cancer
Interventions
Procedure: central neck dissection
Registration Number
NCT04076514
Lead Sponsor
Assiut University
Brief Summary

The benefits of prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC). This study main goal is to investigate benefits of prophylactic central neck dissection in clinically node-negative papillary thyroid carcinoma.

Detailed Description

Papillary thyroid carcinoma (PTC) is the most common type of differentiated thyroid carcinoma. Recurrence rate is still high. The standard management is total thyroidectomy. regional lymph node metastasis is noted in recurrent cases. Some studies stated benefits of central neck dissection in orevention of recurrence and others said there is no benefits. so prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC).

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
20
Inclusion Criteria
  • patients with papillary thyroid cancer with clinically node negative.
Exclusion Criteria
  • patients with clinical evidence of nodal metastases.
  • patients with a previous history of thyroidectomy.
  • patients with mixed-type papillary thyroid cancer.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
patients with node negative papillary thyroid carcinomacentral neck dissection-
Primary Outcome Measures
NameTimeMethod
the incidence metastatic lymph node in patients with clinically node-negative thyroid carcinoma who underwent total thyroidectomy with central neck dissection12 months

numbers of positive histopathological lymph node biopsies postoperative

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Ahmed Kamel

🇪🇬

Asyūţ, Asyut, Egypt

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