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Investigation of the Effect of Asvard Capsules on the Adults Reflux

Phase 2
Conditions
Reflux.
Gastro-esophageal reflux disease
Registration Number
IRCT20230226057538N1
Lead Sponsor
Gorgan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
144
Inclusion Criteria

The Reflux patients with the age between 18-60 years olds.
The patients have to been infected with the Reflux disease for 6 months ago and it get shown Reflux symptoms twice in the week.
Reflux diagnosis would be base on ROME IV symptoms and endoscopy without specific pathological findings
All subjects must be without Helicobacter pylori infection.
All subjects don't have been any antibiotics and PPIs in the last month.
Without underlying diseases such as heart failure; kidney and liver failure; cirrhosis; Diabetes, thyroid disorders, etc.
Without cigarette smoking, drugs abuse or alcohol
Without taking NSAIDs or Aspirin
Without pregnancy or breastfeeding

Exclusion Criteria

If patient use a drug with a direct impact on the digestive system.
If patient is infected to underlying diseases.

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Analysis of Reflux symptoms. Timepoint: Days: zero, 21, 42 and 56. Method of measurement: Questionnaires and standard measurement scales.
Secondary Outcome Measures
NameTimeMethod
Investigation of likely side effects after drug administration. Timepoint: Days: 21, 42 and 56. Method of measurement: Visual Analogue Scale.
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