Comparison of the effect of Azitromycin and co- Amoxiclav in the treatment of adult sinusitis.

Not Applicable

• Conditions: Acute sinusitis.; Acute sinusitis, unspecified

• Registration Number: IRCT201505106252N7
• Lead Sponsor: Shahrekord University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Existing at least two major criteria or one major criteria and two minor criteria that lasting at least 7 days and at most 28 days. Major criteria are: facial pain or pressure; facial fullness or congestion; nasal obstruction; purulent rhinorrhea or postnasal discharge; loss of smell; fever. Minor criteria: headache; halitosis; fatigue; toothache; cough; otalgia; fullness of ear.
Exclusion criteria: Patients with chronic sinusitis; patients with recurrent sinusitis; patients with anatomical disorders( severe septal deviation; cleft palate; nasal poliposis; patients with chronic disorders (severe hepatic disease; renal disease; heart disease and asthma); women in pregnancy and breast feeding; history of sensitivity to co_ amoxiclav or azitromycin; patients with cilliary dysfunction; cystic fibrosis; congenital or acquired immune deficiency (HIV; diabetes); complications of sinusitis; antibiotic consumption in last one month; patients less than 12 years old or more than 65 years old.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Facial pain. Timepoint: fifth day, tenth day. Method of measurement: clinical evaluation.;Feeling of fullness or congestion of the face. Timepoint: fifth day, tenth day. Method of measurement: clinical evaluation.;Nasal obstruction. Timepoint: fifth day, tenth day. Method of measurement: clinical evaluation.;Purulent discharge of nose or postnasal discharge. Timepoint: fifth day, tenth day. Method of measurement: clinical evaluation.;Loss of smell. Timepoint: fifth day, tenth day. Method of measurement: clinical evaluation.;Fever. Timepoint: fifth day, tenth day. Method of measurement: cheking with termometer.

Secondary Outcome Measures

Name	Time	Method
Headache. Timepoint: fifth day, tenth day. Method of measurement: history.;Hallitosis. Timepoint: fifth day, tenth day. Method of measurement: history.;Fatigue. Timepoint: fifth day, tenth day. Method of measurement: history.;Toothache. Timepoint: fifth day, tenth day. Method of measurement: history.;Cough. Timepoint: fifth day, tenth day. Method of measurement: history.;Otalgia or feeling of fullness in the ear. Timepoint: fifth day, tenth day. Method of measurement: history.