NL-OMON32142已完成2 期
A Phase 1b/2 Study of AMG 655 in Combination With Doxorubiicn for the First-Line Treatment of Locally Advanced or Metastatic, Unresectable Soft Tissue Sarcoma - Treatment of Locally Metastatic, Unresectable Soft Tissue Sarcoma
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- Amgen
- 入组人数
- 5
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Histologically or cytologically confirmed soft tissue sarcoma
- •Locally advanced, recurrent, or metastatic, unresectable disease
- •Intermediate or high grade disease (grade 2 or 3 according to the Federation Nationale des Centres de Lutte Contre le Cancer (FNCLCC) grading sysem)
排除标准
- •The following tumor types ar not eligible: Alveolar soft part sarcoma, Clear cell sarcoma (melanoma of soft parts), Chondrosarcoma, Desmoid tumor, Desmoplastic small round cell tumor, Embryonal rhabdomyosarcoma, Ewing sarcoma / Primitive neuroectodermal tumor (PNET), Gastrointestinal stroma tumor (GIST), Kaposi sarcoma, Mesothelioma, Mixed mesodermal tumor, Neuroblastoma, Osteosarcoma.
- •History or known presence of uncontrolled central nervous system (CNS) metastasis
- •Prior Chemotherapy or investigational agent(s) for the treatment of locally advanced or metastatic, unresectable soft tissue sarcoma (prior neo-adjuvant or adjuvant therapy is allowed, provided there was no disease progression with 6 months after completion of treatment)
研究者
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