Comparison of the effects of oral hygiene instruction and periodontal treatment on patients with Type 2 diabetes mellitus

Not Applicable

• Conditions: Diabetes Mellitus, Periodontital disease

• Registration Number: JPRN-UMIN000013278
• Lead Sponsor: Okayama University Hospital

Brief Summary

Forty participants were enrolled. The periodontal treatment group (n = 20) received non-surgical periodontal therapy. The control group (n = 17) received only oral hygiene instructions. Changes in HbA1c in the periodontal treatment group were not significantly different with those in the control group at 3 and 6 months. Mean probing pocket depth, clinical attachment level, systemic oxidative stress balance and QOL significantly improved in the periodontal treatment group compared to the control group at 3 months. In the subgroup analysis (moderately poor control of diabetes), the decrease in HbA1c levels in the periodontal treatment group was significantly greater than that in the control group at 3 months.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-04-01
• Study Completion: 2016-08-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Not provided

Exclusion Criteria

Undergoing dental treatment Under pregnancy Being diagnosed as unsuitable subjects

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
glycated hemoglobin (HbA1c)

Secondary Outcome Measures

Name	Time	Method
fasting plasma glucose, glicated albumin, creatinine, cytokines, oxidative stress, and QO