Investigation of Hand Functions and Related Parameters in People With Multiple Sclerosis
- Conditions
- Multiple Sclerosis
- Registration Number
- NCT04933110
- Lead Sponsor
- Uğur OVACIK
- Brief Summary
The upper extremity in people with Multiple Sclerosis (pwMS) has become a more popular research topic in recent years, with the increase in studies reporting widespread involvement. The aim of our study was to evaluate the upper extremity from multiple perspectives in early stage pwMS, to identify problems by comparing them with healthy individuals, and to examine the relationship of problems with activity and participation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 90
- MS diagnosis according to McDonald criteria
- Relapsing Remitting MS clinical course type
- 18-65 age range
- Being able to understand and read Turkish
- Having an MS attack in the last 3 months
- To have done regular exercise for the upper extremity in the 6 months before starting the study
- Having different neurological, orthopedic or cardiac problems other than MS
- Being addicted to alcohol or drugs
- Getting a score below 24 on the Mini Mental Test Scale
- Having a spasticity of 3 or more according to the Modified Ashworth Scale
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Motor Activity Log-28 baseline (on the predetermined assessment day) To assess for performance of activity. Score range 0-5 point, a high score indicates good upper extremity use frequency and quality of movement during activity.
Community Integration Questionnaire baseline (on the predetermined assessment day) To assess participation. The total score ranges from 0-29, and the higher the score, the higher the individual's participation in society is considered.
Minnesota Manual Dexterity Test baseline (on the predetermined assessment day) To assess upper extremity function. Completing the test in a short time (seconds) indicates better upper extremity function.
ABILHAND baseline (on the predetermined assessment day) To assess for performance of activity. Score range 0-46 point, higher scores mean a better outcome.
Nine Hole Peg Test baseline (on the predetermined assessment day) To assess upper extremity function. Completing the test in a short time (seconds) indicates better upper extremity function.
- Secondary Outcome Measures
Name Time Method Pinchmeter baseline (on the predetermined assessment day) To assess pinch strength. Higher scores indicate better muscle strength.
Symbol Digit Modalities Test baseline (on the predetermined assessment day) To assess cognitive level. A higher score indicates better cognitive level.
Fatigue Severity Scale baseline (on the predetermined assessment day) To assess the severity of fatigue. Score range 1-7 point, a higher score indicates more severe fatigue.
Hand Held Dynamometer baseline (on the predetermined assessment day) To assess upper extremity muscle strength. Higher scores indicate better muscle strength.
Hand Dynamometer baseline (on the predetermined assessment day) To assess grip strength. Higher scores indicate better muscle strength.
Tuning fork baseline (on the predetermined assessment day) To assess deep sense. A higher score indicates better sensitivity.
Hospital Anxiety and Depression Scale baseline (on the predetermined assessment day) To assess anxiety and depression. The total score ranges from 0 to 21 for each of the two subscales. A higher score indicates more severe anxiety and depression.
Aesthesiometer baseline (on the predetermined assessment day) To assess two-point discrimination. A higher score indicates worse sensitivity.