Research and development of new technology and new scheme for preserving fertility of gynecological tumor

Obstetrics and Gynecology Department, Peking University People's Hospital0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•(1) Aged <= 40 years, have strong desire to have children;
•(2) atypical hyperplasia of uterus, endometrial cancer progesterone treatment remission;
•(3) endometrial cancer iag1-iag2 stage, endometrial atypical hyperplasia;
•(4) imaging examination confirmed that the tumor was confined to the endometrium;
•(5) estrogen and progesterone receptor (ER, PR) were positive;
•(6) peripheral blood CA125;
•(7) no contraindication of progesterone treatment;
•(8) evaluation of reproductive function before treatment, no other factors of fertility disorders;
•(9) after complete remission, when the dominant follicle in follicular phase reached 15 mm, the endometrial thickness was less than 7.0 mm;
•(10) acupuncture treatment was used to improve the endometrial receptivity after preserving reproductive function;
•(11) informed consent was signed, and good follow-up conditions were available.

•(1) Patients with severe medical diseases and severe impairment of liver and kidney function;
•(2) patients with endometrioid adenocarcinoma whose pathological stage or grade is higher than stage IA G1, or with deep myometrial invasion, cervical invasion or distant metastasis in pelvic and abdominal cavity;
•(3) patients with drug allergy and contraindications;
•(4) patients with other types of endometrial cancer or other malignant tumors of reproductive system; patients with breast cancer or other malignant tumors He can not use progesterone hormone dependent tumor;
•(5) require hysterectomy or other methods of treatment except conservative treatment;
•(6) deep vein thrombosis, stroke, myocardial infarction;
•(7) allergic constitution or allergic to acupuncture.

发起方

Obstetrics and Gynecology Department, Peking University People's Hospital