Allogeneic Bone Marrow and Mesenchymal Stem Cell Transplantation for patients with severe Hypophosphatasia
Phase 2
- Conditions
- Hypophosphatasia
- Registration Number
- JPRN-UMIN000003828
- Lead Sponsor
- Shimane University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 5
Inclusion Criteria
Not provided
Exclusion Criteria
1. Objective Patients with non-severe HPP Patients wothuout inclusion criteria 2. BM donor Patients wothuout inclusion criteria
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rescuing the patients with severe hypophospatasia
- Secondary Outcome Measures
Name Time Method Height, Weight, alkaline phosphatase(ALP), bone-type ALP, Ca, P, substrates of ALP(phosphoethanolamine, pyridoxal 5-phosphate), Neutrohpil ALP score, X-ray of bone and chest, bone density, ability of bone formation