CTRI/2025/09/095057尚未招募4 期
Comparison of preoperative oral melatonin and alprazolam on postoperative pain management in patients undergoing elective abdominal hysterectomy.
Abhirami NP1 个研究点 分布在 1 个国家目标入组 102 人开始时间: 2025年9月29日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- Preoperative oral melatonin significantly reduces postoperative pain scores compared to those receiving oral aprazolam as premedication in patients undergoing elective abdominal hysterectomy.
研究概览
简要总结
This is a prospective randomized comparative study conducted in the Department of Anesthesiology, Government Medical College, Kozhikode. The study aims to compare the effects of preoperative oral melatonin and alprazolam on postoperative pain management in patients undergoing elective abdominal hysterectomy. Eligible patients will be randomized into two groups and assessed for postoperative pain and analgesic requirements as per the study protocol.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- Female
入选标准
- •Female patients aged more than thirty years but less than sixty five years.
- •Patients undergoing elective abdominal hysterectomy.
- •Patients belonging to American Society of Anaesthesiologists physical status class one or two.
- •Height between one hundred fifty centimeter and one hundred seventy centimeter.
- •Body mass index between eighteen and thirty kilogram per square meter.
排除标准
- •Patients with contraindications to regional anaesthesia.
- •Patients with mental impairment.
- •Patients with history of chronic pain.
- •Patients with history of psychiatric illness or those taking psychotropic drugs in the past or present.
- •Patients posted for emergency surgeries.
结局指标
主要结局
Preoperative oral melatonin significantly reduces postoperative pain scores compared to those receiving oral aprazolam as premedication in patients undergoing elective abdominal hysterectomy.
时间窗: 6,12,24 hours
次要结局
- Preoperative oral melatonin reduces anxiety more compared to preoperative oral alprazolam.(30 minutes before surgery)
- Preoperative oral melatonin providesbetter sedation than oral alprazolam.(6,12 hours)
研究者
Abhirami NP
Government Medical College Kozhikode
研究点 (1)
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