Effect of Sacubitril-Valsartan versus angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blocker (ARB) on left ventricular ejection fraction in patient with heart failure
Phase 3
Recruiting
- Conditions
- Heart failure.Heart failure
- Registration Number
- IRCT20120215009014N503
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 225
Inclusion Criteria
Age 18 to 80 years
Heart failure
Exclusion Criteria
Severe coronary disease
Valvular heart disease
Pulmonary thromboembolism
Congenital heart disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Average blood pressure. Timepoint: Every 2 weeks for 6 months after the intervention. Method of measurement: Using a sphygmomanometer.;Mean serum creatinine. Timepoint: Every 2 weeks for 6 months after the intervention. Method of measurement: By taking blood samples.;The average quality of life score. Timepoint: Every 2 weeks for 6 months after the intervention. Method of measurement: Using the New York Heart Association (NYHA) questionnaire.;Left heart ejection fraction. Timepoint: Every 2 weeks for 6 months after intervention. Method of measurement: With echocardiography.;The frequency and duration of hospitalization. Timepoint: Within 6 months after the intervention. Method of measurement: By examining the medical record.;The occurrence of death. Timepoint: Within 6 months after the intervention. Method of measurement: By examining the medical record.
- Secondary Outcome Measures
Name Time Method