CTRI/2021/01/030246尚未招募不适用
Evaluation of host and microbial factors that lead to urosepsis in women of reproductive age group: A case control study
MANIPAL COLLEGE OF HEALTH PROFESSIONS1 个研究点 分布在 1 个国家目标入组 170 人开始时间: 2021年1月14日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 170
- 试验地点
- 1
- 主要终点
- pap, hly A and iut A gene in genetically similar E. coli strains
研究概览
简要总结
The present case control study is to estimate the host and microbial factors that lead to development of urosepsis in women of reproductive age group having urinary tract infections due to Escherichia coli. The study will be conducted in 85 patients with urinary tract infection and 85 patients with urosepsis visiting/admitted in Kasturba Medical College, Manipal. The primary outcome will be the genetic markers of E. coli causing urosepsis, including pap A, Hly A and iut A along with serum IgG2 levels in ng/ml.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 49.00 Year(s)(—)
- 性别
- Female
入选标准
- •Urinary and blood isolates of E.
- •coli from women with age ranging from 18 to 49 years attending Kasturba hospital with complaints of UTI or developed UTI after admission to hospital.
排除标准
- •UTI confirming with microbiological culture with bacteria other than E.
结局指标
主要结局
pap, hly A and iut A gene in genetically similar E. coli strains
时间窗: 4 years
Serum IgG2 levels in g/L
时间窗: 4 years
次要结局
- Identification host factors that causes lead to the progression of urosepsis(4 years)
研究者
研究点 (1)
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