跳至主要内容
临床试验/CTRI/2021/01/030246
CTRI/2021/01/030246尚未招募不适用

Evaluation of host and microbial factors that lead to urosepsis in women of reproductive age group: A case control study

MANIPAL COLLEGE OF HEALTH PROFESSIONS1 个研究点 分布在 1 个国家目标入组 170 人开始时间: 2021年1月14日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
170
试验地点
1
主要终点
pap, hly A and iut A gene in genetically similar E. coli strains

研究概览

简要总结

The present case control study is to estimate the host and microbial factors that lead to development of urosepsis in women of reproductive age group having urinary tract infections due to Escherichia coli. The study will be conducted in 85 patients with urinary tract infection and 85 patients with urosepsis visiting/admitted in Kasturba Medical College, Manipal. The primary outcome will be the genetic markers of E. coli causing urosepsis, including pap A, Hly A and iut A along with serum IgG2 levels in ng/ml.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 49.00 Year(s)(—)
性别
Female

入选标准

  • •Urinary and blood isolates of E.
  • •coli from women with age ranging from 18 to 49 years attending Kasturba hospital with complaints of UTI or developed UTI after admission to hospital.

排除标准

  • •UTI confirming with microbiological culture with bacteria other than E.

结局指标

主要结局

pap, hly A and iut A gene in genetically similar E. coli strains

时间窗: 4 years

Serum IgG2 levels in g/L

时间窗: 4 years

次要结局

  • Identification host factors that causes lead to the progression of urosepsis(4 years)

研究者

发起方
MANIPAL COLLEGE OF HEALTH PROFESSIONS
申办方类型
Research institution and hospital

研究点 (1)

Loading locations...

相似试验