Associations of Nighttime Light Exposure During Pregnancy With Neonatal Jaundice：a Multi-centre Prospective Study in China
- Conditions
- Jaundice, Neonatal
- Registration Number
- NCT03805165
- Lead Sponsor
- Guangdong Women and Children Hospital
- Brief Summary
Make a neonatal jaundiced nomogram on Chinese jaundice data by joinning the major neonate centers all around China.
- Detailed Description
This was a multi-centre prospective study. All infants included were born in 8 hospitals in the southern, eastern, northern, western and central regions of mainland China in 2019. A total of 20839 transcutaneous bilirubin(TCB) measurements were performed with 2977 neonates at designated time points. The mean NTL exposure during pregnancy was respectively calculated based on each participant's residential address over the study course. The primary outcome was whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life. The effect of maternal nocturnal light exposure on neonate jaundice analyzed with lasso regression and random forest machine learning methods.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2977
gestational age more than 35 weeks(≥35) -
all kinds of congenital diseases, infants with pathologic jaundice
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hour-specific Transcutaneous Bilirubin Level 1 year make neonatal jaundiced nomogram base on the hour-specific transcutaneous bilirubin data
whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life 2019 whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Jie Yang
🇨🇳Guangzhou, Guangdong, China