Outcomes of Severe Osteoporotic Fractures Hospitalized in France: the CROSS Cohort
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 912
- 试验地点
- 1
- 主要终点
- Number of new severe fracture over 2 years
研究概览
简要总结
The purpose of this study is to determine the outcomes of severe osteoporotic fractures hospitalized in France, the risk of incident severe fracture at 2 years and 5 years and the risk of mortality over 2 and 5 years.
详细描述
In France, the burden of osteoporotic fractures has been studied using cross sectional data from the French hospital national database. The availability of fracture liaison service in the main French cities allows the recruitment of a high number of these targeted patients. A large national multicenter, longitudinal, prospective cohort of patients hospitalized for severe osteoporotic fracture, the CROSS cohort ("Cohorte sur les Risques d'une OStéoporose Sévère"), in order to update data on prognosis (refracture, mortality), epidemiology and of severe osteoporotic fractures.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women aged above 60 years, living in France and hospitalized for severe fragility fractures in response to low-energy trauma (e.g., a fall from standing height).
- •Vertebral fractures have to be confirmed by an X ray examination.
- •To be eligible for the study the patient has to be included and interviewed within 12 weeks of the fracture event's diagnosis. Note : patients in guardianship or curatorship can be included in this protocol.
- •Informed and free consent given and form signed and dated
排除标准
- •Non severe fracture (for example wrist fracture), pathological fractures, high trauma fractures and per prosthetic fractures.
- •Non registration with a social security scheme (holder or beneficiary).
结局指标
主要结局
Number of new severe fracture over 2 years
时间窗: 2 years
To assess the incidence of new severe fracture over 2 years in patients hospitalized for a severe fracture
次要结局
- Number of new severe fracture over 5 years(5 years)