To Study the Efficacy of Ropivacaine 0.2 percentage vs Ropivacaine 0.2 percentage with Nalbuphine for Post operative Analgesia in appendicectomy patients by Transversus Abdominis Plane Block
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- 1.Post operative pain score(visual analog score-VAS) will be assessed
研究概览
简要总结
Regional anaesthesia techniques are gaining more acceptance as a part of multi model analgesia. Multimodal analgesia includes use of opioids,non steroidal anti-inflammatory drugs, paracetamol infusion and regional anaesthetic techniques such as epidural block, local infiltration or nerve blocks.
Also high doses of opioids cause significant risks such as post-operative nausea and vomiting, Sedation, sleep disturbances, urinary retention and respiratory depression in post-operative patients.
By effectively managing post-operative pain with proper analgesia helps to attenuate surgical stress response, decreased perioperative morbidity and improves surgical outcome.
Peripheral Nerve blocks such as transversus abdominis plane (TAP) block have been described in the literature as means to alleviate pain due to abdominal wall incision.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 21.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients with American society of Anaesthiologist’s physical status class 1&2 2.Patients posted for uncomplicated open Appendicectomy surgeries 3.Patients aged between 21-65 years of both genders who upon being explained the procedure are willing to participate in the study.
排除标准
- •complicated appendectomies
- •Appendicular mass/abscess.
- •Skin infection at Puncture site.
- •Allergy to local anaesthetics.
- •Preoperative opioid and non-steroidal drug treatment for chronic pain treatment
- •Patients with blood dyscrasias, use of introoperative opiate analgesics, patients with significant hepatic, renal, cardiovascular, pulmonary, metabolic, psychiatric disorders.
结局指标
主要结局
1.Post operative pain score(visual analog score-VAS) will be assessed
时间窗: 30min,1 hr,4hr,8hr,12hr,16hr,20hr and 24hr.
2. to study postoperative Analgesic duration, and analgesic pattern with 0.2%Ropivacaine
时间窗: 30min,1 hr,4hr,8hr,12hr,16hr,20hr and 24hr.
3. To study, post operative analgesic duration, and analgesic pattern with 0.2% Ropivacaine with Nalbuphine
时间窗: 30min,1 hr,4hr,8hr,12hr,16hr,20hr and 24hr.
次要结局
- 1)To study, side-effects, if any.(2)To study additional post-operative analgesic requirement)
研究者
Parshant Bansal
Shri Bhausaheb Hire Government Medical college