Role of gastrointestinal hormones and bile acids on microbiota in bariatric surgery with different degrees of malabsorption

Fondo de Investigaciones Sanitarias - Instituto de Salud Carlos III-FEDER (PI-16/01655)0 个研究点目标入组 96 人开始时间: 2018年2月24日最近更新: 2018年3月19日

适应症

试验速览

暂无简介。

•1. Patients on the bariatric surgery waiting list
•2. Caucasian men and women aged 18-65
•3. BMI = 40 kg/m2 or = 35 kg/m2 with at least one major comorbidities (Type 2 diabetes, hypertension, hyperlipemia, sleep obstructive apnea)
•4. Absence of serious disease (chronic kidney disease, liver disease, neurological disease)
•5. Absence of psychiatric pathology
•6. Ability to understand the mechanisms involved in the surgery that will be proposed
•7. Written informed consent to participate in the study
•Inclusion criteria for the control group:
•1. Caucasian men and women, aged 18-65 years (matched with patients)
•2. BMI 20-29.9 kg/m2
•3. No pregnant and lactating women
•4. Absence of major comorbidities (Type 2 diabetes, hypertension, hyperlipidemia, sleep obstructive apnea)
•5. Absence of serious diseases (chronic kidney or liver disease, inflammatory diseases, neurological diseases, cancer, AIDS)
•6. Absence of psychiatric disorders
•7. Written informed consent to participate in the study

•1. Systemic disease not associated with obesity (inflammatory bowel disease, inflammatory rheumatic disease)
•2. Hepatitis C, known cirrhosis (or discovered during the study)
•4. Drug and/or alcohol abuse
•5. Eating disorders

发起方

Fondo de Investigaciones Sanitarias - Instituto de Salud Carlos III-FEDER (PI-16/01655)