Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration

Not Applicable

Recruiting

• Conditions: Horizontal Ridge Deficiency
• Interventions: Procedure: Vascularized inter-positional periosteal connective tissue flap

• Registration Number: NCT05813340
• Lead Sponsor: Cairo University

Brief Summary

this study compares 2 techniques in guided bone regeneration for horizontal ridge augmentation in aesthetic zone

Detailed Description

Guided bone regeneration is a technique for ridge augmentation using membranes The membrane of GBR is an essential component of treatment as it has some important characteristics manageability, space-making ability, and adequate mechanical, physical properties, and biocompatibility Collagen membranes are the most commonly used and can inhibit soft tissue growth in bone defects and achieve better wound healing and bone regeneration.

on the other hand, a Vascularized inter-positional periosteal connective tissue flap is a flap that has been used as a substitute for the collagen membrane with promising results. Vascularized inter-positional periosteal connective tissue flap (VIPCTF) may have many advantages over traditional collagen membranes such as; high vascularity, decreased cost (as it may substitute membrane), providing an increase in soft tissue thickness, and reusability.

So Evaluation of effect of vascularized interpositional periosteal connective tissue flap on horizontal ridge augmentation grafting of the anterior maxilla in comaprison with the collagen membranes

Study Timeline

• Study Start: 2023-01-01
• Status Verified: 2023-04
• Study First Submitted: 2023-04-02
• Study First Submitted QC: 2023-04-02
• Last Update Submitted: 2023-04-02
• Study First Posted: 2023-04-14
• Last Update Posted: 2023-04-14
• Primary Completion: 2023-06-01
• Study Completion: 2023-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Patients with a horizontal defect in anterior and premolar areas of the maxilla (aesthetic zone).

Exclusion Criteria

• poor oral hygiene
• radiation therapy of head and neck cancer
• intraoral soft and hard tissue lesions
• Heavy smoking
• Bone pathology

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
vascularized interpositional periosteal connective tissue flap	Vascularized inter-positional periosteal connective tissue flap	Vascularized inter-positional periosteal connective tissue flap (VIPCTF) may have many advantages over traditional collagen membranes such as; high vascularity, decreased cost (as it may substitute membrane), providing an increase in soft tissue thickness, and reusability.
collagen membrane	Vascularized inter-positional periosteal connective tissue flap	Collagen membranes are the most commonly used and can inhibit soft tissue growth in bone defects, They achieve better wound healing and bone regeneration.

Primary Outcome Measures

Name	Time	Method
Amount of bone width gain (horizontal augmentation)	6 months	bone width gain is measured in millimeters by Cone beam computed tomography

Secondary Outcome Measures

Name	Time	Method
Percentage of bone formation in the bone biopsy	6 months	Area percentage of newly formed bone is measured through histomorphometric analysis

Trial Locations

Locations (1)

Faculty of dentistry Cairo university; 🇪🇬 Cairo, Egypt