Study for the mechanisms of recurrent urinary tract infections with postmenopausal women with Zhuolin Granules from the perspective of microecological changes

Phase 1

Recruiting

• Conditions: Recurrent Urinary Tract Infection

• Registration Number: ITMCTR1900002671
• Lead Sponsor: Changzhou Affiliated Hospital of Nanjing University of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

1. meeting the diagnosis criteria of urinary tract infection;
2. symptomatic urinary tract infection (urinary frequency, urgency, dysuria; at least two symptoms);
3. had a documented history of three or more culture-confirmed symptomatic episodes of uncomplicated UTI in the previous year;
4. menopausal (without menstruation for at least 12 months);
6. sign the informed consent.

Exclusion Criteria

1. Complicated urinary tract infections caused by urinary tract obstruction, indwelling catheter, diabetes mellitus and impaired immune function;
2. Urethral syndrome, asymptomatic bacteriuria;
3. Combined with serious heart, liver, kidney, hematopoietic system, endocrine, respiratory system and other diseases, malignant tumors or serious diseases affecting their survival;
4. Non-bacterial infections (fungi, mycoplasma, chlamydia, parasites);
5. Allergic constitution, or known drug allergy patients used in this test;
6. Immune stimulation therapy was administered within one month before admission;
7. Patients participated in clinical trials of other drugs or antibiotics or probiotics were used in previous three months.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
urine culutre;Urinalysis;Urine microbiota;Fecal microbiota;