National Registry and Cohort Study of Pulmonary Vascular Disease
- Conditions
- Pulmonary Arterial Hypertension
- Registration Number
- NCT05368467
- Brief Summary
This is a observational、multicenter, prospective cohort study for patients with pulmonary hypertension (PH). The purposes of this study were to evaluate the etiology、clinical characteristics、treatment modalities, and outcomes of patients with PH;also to set up registration system of PH in China, to build a database of Chinese PH, to establish a web-based international standard data acquisition system for PH and a multicenter clinical research platform. The results of the study will provide a basis for the future national health policy for prevention and treatment of PH.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 1000
- Newly diagnosed or previously diagnosed patients with PH.
- Documentation of mean pulmonary arterial pressure (mPAP) >20 mm Hg by right heart catheterization, performed at any time prior to study enrollment.
- Have not had documentation of hemodynamic criteria for PH by right heart catheterization at some time preceding study entry and following development of symptoms associated with PH.
- Do not meet the required hemodynamic criteria for entry into the study.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All-cause Death 5 years
- Secondary Outcome Measures
Name Time Method Number of Participants with Clinical Worsening 5 years Clinical worsening during follow-up was defined as worsening PAH or atrial septostomy or listing for lung transplantation or all-cause death. Worsening PAH required the presence of worsening PAH symptoms and a decrease in 6-minute walk distance greater than 15% from baseline and the requirement for additional PAH treatments (all three conditions had to be present).
Related Research Topics
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Trial Locations
- Locations (13)
Guangdong Provincial Peoples Hospital
🇨🇳Guangzhou, Guangdong, China
Nanjing First Hospital
🇨🇳Nanjing, Jiangsu, China
General Hospital of Tianjin Medical University
🇨🇳Tianjin, Tianjin, China
Beijing Anzhen Hospital of Capital Medical University
🇨🇳Beijing, China
China-japan Friendship Hospital
🇨🇳Beijing, China
Xiangya Second Hospital, Central South University
🇨🇳Changsha, China
West China Hospital, Sichuan University
🇨🇳Chendu, China
Nanjing Drum Tower Hospital
🇨🇳Nanjing, China
General Hospital of Northen Theater of Command
🇨🇳Shenyang, China
Tongji Hospital, Huazhong University of Science and Technology
🇨🇳Wuhan, China
Scroll for more (3 remaining)Guangdong Provincial Peoples Hospital🇨🇳Guangzhou, Guangdong, ChinaCaojing ZhangContact