Slough in Acute or Chronic Wounds for the Diagnosis of Microbiology Cultivation
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 131
- 试验地点
- 1
- 主要终点
- cohen's k coefficient of Gram Stain between Slough and Swap Specimens
研究概览
简要总结
Slough was a visible indicator of biofilm, which was the most available specimen from acute and chronic wounds. However, studies believed that slough were poorly accurate, and that the Levine swab was more recommended for sampling bacterial culture. This study aimed to compare slough with swab sample and analyze the consistency.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with acute and chronic wounds who were first seen at the Wound Care Centre of Peking University Third Hospital from October 2022 to October 2023;
- •Patients who have followed the wound sample collection SOP to simultaneously take wound swabs and putrefactive samples and send them for bacterial culture;;
- •Patients aged 18 years or older;
排除标准
- •Patients who had been taken only one of the wound samples, either swab or slough;
- •The swab collection did not meet the deifinitions for the exudate method or the Levine technique；
- •Bacterial culture profile was incomplete didn't meet the requirement of the trial.
结局指标
主要结局
cohen's k coefficient of Gram Stain between Slough and Swap Specimens
时间窗: Day 0, patients' the first site in wound healing center
compare the difference of Gram Stain after bacterial culture between Slough and Swap Specimens, by using statistics of cohen's k coefficient，values of κ from The κ coefficients in 0.81 to 1 waeres interpreted as excellentalmost perfect concordance, with 0.61 to 0.80 asrepresented substantial, 0.41 to 0.60 as mean moderate, 0.21 to 0.40 as fair, and 0 to 0.20 as slight.
次要结局
- cohen's k coefficient of Common pathogens between Slough and Swap Specimens(Day 0, patients' the first site in wound healing center)
- agreements in microbiology cultivation between slough and swap(Day 0, patients' the first site in wound healing center)
研究者
Long Zhang
Professor, Head of Wound Healing Center
Peking University Third Hospital