Efficacy of Buprenorphine in the Methamphetamine Dependency

Phase 2

• Conditions: Methamphetamine dependency.; Mental and behavioural disorders due to use of other stimulants, including caffeine

• Registration Number: IRCT2013112315499N1
• Lead Sponsor: Vice chancellor for research, Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

1. Ability to reading and writing in Persian;
2. Age between 18 and 55 years old;
3. All participants with diagnosis of methamphetamine dependency according to the DSM IV criteria;
4. Agreement to participating in study;
Exclusion criteria:
1. Participants currently enrolled in another investigational device or drug trial or previously enrolled (within last 30 days) in investigative research of a device or pharmaceutical agent;
2. Co - use of methamphetamine and methadone;
3. Inability to tolerate buprenorphine;
4. Presence of any liver failure such as hepatitis;
5. History of any lung disease;
6. Presence of any thyroid disease such hypothyroidism or hyperthyroidism;
7. Presence of adrenal gland disease such as addison disease;
8. Presence of kidney failure such as CRF, ARF, etc.
9. Presence of heart failure;
10. Presence of prostatic hyperplasia or urethra tightness;
11. History of epilepsy or uncontrolled seizures;
12. Presence of any cancer;
13. Pregnancy;
14. Any evidences to confirm participants sail buprenorphine outside the addiction treatment center or any evidences to confirm participants will not use buprenorphine;
15. No acceptance to enroll in or continue the study;

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Existence of methamphetamine in urine samples. Timepoint: three times in a week in first three months, one time a week in second three months of following. Method of measurement: Urine rapid test kit (Methamphetamine).