Clinical Study on the Effect of Preoperative Serum Biomarkers on the Prognosis of Gastric Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 3,400
- 主要终点
- the incidence of gastric cancer
研究概览
简要总结
Gastric cancer is one of the most common cancers worldwide, especially in East Asia. Although surgery remains the main treatment, patients may experience postoperative complications and have varying long-term survival outcomes. Early identification of high-risk patients before surgery is important for improving treatment decisions and patient management.
This study aims to develop a prediction model based on routinely available preoperative blood test results and clinical characteristics to estimate the risk of postoperative complications and long-term survival in patients with gastric cancer. The model will be developed and validated using data from multiple medical centers.
By using easily accessible clinical information, this study seeks to provide a practical tool to help clinicians better assess patient risk before surgery, support personalized treatment planning, and improve overall patient outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients aged ≥18 years;
- •patients diagnosed with gastric cancer by pathological biopsy before surgery;
- •patients without chemotherapy, radiotherapy, targeted and immunotherapy before enrolment;
- •willing to participate in this study and sign the informed consent;
- •complete clinical data.
排除标准
- •patients with other primary malignant tumours other than gastric cancer;
- •patients with systemic diseases such as severe cardiopulmonary insufficiency that affect the choice of treatment plan;
- •patients who are not suitable for enrolment as assessed by the investigator;
- •incomplete clinical data.
结局指标
主要结局
the incidence of gastric cancer
时间窗: From 18 years old until the developing gastric cancer, through study completion, an average of 5 year.
the diagnosis time of gastric cancer
次要结局
未报告次要终点
研究者
Dong Peng
Principal Investigator
First Affiliated Hospital of Chongqing Medical University