Impact of macrophage polarization on the efficacy of surgical therapy of peri-implantitis
- Conditions
- PeriimplantitisK10.28
- Registration Number
- DRKS00030110
- Lead Sponsor
- Poliklinik für Zahnärztliche Chirurgie und Implantologie, Zentrum für Zahn-, Mund- und Kieferheilkunde (Carolinum)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
(1) minimum age of 18 years old;
(2) partially/totally edentulous patients exhibiting titanim dental implants diagnosed with moderate or advanced peri-implantitis;
(3) presence of keratinized mucosa = 2 mm
(4) intrabony defect depth = 3mm;
(5) plaque index <1 (Löe, 1967) prior to surgery.
Exclusion Criteria
(1) untreated periodontal disease and insufficient oral hygiene;
(2) pregnant or lactant women;
(3) autoimmune or/and inflammatory diseases;
(4) uncontrolled diabetes (HbA1c>7);
(5) corticosteroid therapy.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the influence of the M1/M2 ratio on the clinical outcomes following reconstructive surgical therapy of moderate to advanced peri-implantitis lesions
- Secondary Outcome Measures
Name Time Method