Dopaminergic Effects on Brown Adipose Tissue: the DEBAT trial - DEBAT

Academisch Medisch Centrum0 个研究点目标入组 16 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•Male Caucasian Origin 18-30 years old BMI range 19-25kg/m2 Subjects should be able and willing to give informed consent.

•Renal failure (creatinine >135 mmol/L), liverfailure (AST/ALT > 3 times higher than the normal upper value), Daily use of prescription medicine or drug use, Prior participation in a research protocol involving radiation exposure in the last 2 years, Known hypersensitivity to bromocriptine, domperidone maleate or other ergot alkaloids. Uncontrolled hypertension. Known history of coronary artery disease, or other severe cardiovascular conditions (such as a prolonged Qtc-time), or symptoms / history of severe psychiatric disorders. Known cardiac valvulopathy
•Prolactin-releasing pituitary tumour (prolactinoma).Cases where stimulation of the gastric motility could be harmful: gastro-intestinal haemorrhage, mechanical obstruction or perforation.
•Subjects with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.

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