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Clinical Trials/NCT01421641
NCT01421641
Completed
Phase 4

The Effect of Intracervical Lidocaine Injection Versus Topical Lidocaine Gel on the Pain Experienced by Patients Undergoing Tenaculum Application to the Cervix at the Time of an Office Gynecologic Procedure

Oregon Health and Science University1 site in 1 country74 target enrollmentSeptember 2011

Overview

Phase
Phase 4
Intervention
Intracervical Lidocaine Injection
Conditions
Cervical Pain
Sponsor
Oregon Health and Science University
Enrollment
74
Locations
1
Primary Endpoint
Tenaculum Pain
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The purpose of this clinical trial is to evaluate the effect of an intracervical lidocaine injection versus topical lidocaine gel on the pain experienced by patients undergoing tenaculum application to the cervix during office gynecologic procedures. This study will also evaluate how satisfied women are with the method of pain control used.

The researchers hypothesize that:

  1. There is less pain perceived by patients undergoing placement of a tenaculum on the cervix when a lidocaine injection is used compared to a topical lidocaine gel.
  2. Patients are more satisfied with pain control during the overall experience of undergoing tenaculum placement on the cervix when a lidocaine injection is used compared to a topical lidocaine gel.

Detailed Description

Subjects who have already scheduled an IUD insertion or endometrial biopsy will be asked to join this study assessing two pain control interventions at the time of tenaculum application to the cervix during office gynecologic procedures. Only healthy women ages 18 and over with an indication for endometrial biopsy or IUD placement will be recruited. The participants will be randomized to one of two arms: an intracervical lidocaine injection versus topical lidocaine gel. They will be asked to indicate their level of pain and level of satisfaction using a Visual Analog Scale. The primary outcome, pain with tenaculum placement, and the secondary outcome, satisfaction with the experience of tenaculum placement, will be compared between the study groups.

Registry
clinicaltrials.gov
Start Date
September 2011
End Date
May 2012
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Paula Bednarek

MD MPH

Oregon Health and Science University

Eligibility Criteria

Inclusion Criteria

  • Generally healthy women
  • Age 18 and over
  • Indication for endometrial biopsy or IUD placement

Exclusion Criteria

  • Allergy to lidocaine or other local anesthetic
  • Pregnancy, known or suspected
  • Patients who are premedicated with misoprostol
  • Patients with a chronic pain condition for which the patient takes daily pain medication

Arms & Interventions

Intracervical Lidocaine Injection

Injection of 2 cc of 1% lidocaine solution at the anterior lip of the cervix using a standard 22 gauge spinal needle.

Intervention: Intracervical Lidocaine Injection

Topical Lidocaine Gel

Application of 1cc of 2% lidocaine gel to the anterior lip of the cervix with a Q-tip (this amount of lidocaine will be measured out prior to procedure)

Intervention: Topical Lidocaine Gel

Outcomes

Primary Outcomes

Tenaculum Pain

Time Frame: After tenaculum placement

The primary outcome was pain at the time of tenaculum placement. Patient asked to pain scale using 100mm Visual Analog Scale (0mm=no pain, 100mm=worst pain of my life) during after tenaculum placement.

Secondary Outcomes

  • Tenaculum Placement Satisfaction(After placement of the tenaculum)
  • Intervention Pain(after application of randomized intervention)

Study Sites (1)

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