Peer Intervention to Link Overdose Survivors to Treatment (PILOT)

Not Applicable

Completed

• Conditions: Opioid Overdose
• Interventions: Behavioral: Peer Intervention to Link Overdose Survivors to Treatment (PILOT) Peer; Behavioral: Treatment As Usual Peer

• Registration Number: NCT05123027
• Lead Sponsor: Medical University of South Carolina

Brief Summary

The purpose of the Peer Intervention to Link Overdose Survivors to Treatment (PILOT) study is to improve outcomes for individuals after surviving an overdose involving opioids. This study will be comparing the enhanced peer intervention known as PILOT for overdose survivors with treatment as usual (TAU) provided in the Emergency Department.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-10-26
• Study First Submitted QC: 2021-11-04
• Study First Posted: 2021-11-17
• Study Start: 2021-12-28
• Primary Completion: 2024-02-08
• Study Completion: 2024-02-08
• Status Verified: 2025-01
• Results First Submitted: 2025-01-14
• Results First Submitted QC: 2025-01-14
• Last Update Submitted: 2025-01-14
• Results First Posted: 2025-02-07
• Last Update Posted: 2025-02-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Peer Intervention to Link Overdose Survivors to Treatment (PILOT) Peer	Peer Intervention to Link Overdose Survivors to Treatment (PILOT) Peer	-
Peer Intervention to Link Overdose Survivors to Treatment (PILOT) Peer	Treatment As Usual Peer	-
Treatment As Usual Peer	Treatment As Usual Peer	-

Primary Outcome Measures

Name	Time	Method
Number of Self-reported Overdose Risk Behaviors at 180 Days (6 Months) After Index ED Admission	180 days (6 months)	Past month total score on the modified Overdose Risk Behavior Checklist (OBRC) at 180 days (6 months post-randomization) compared between experimental groups. The ORBC was a 13-item scale with 11 of the items used to generate a total score (ranging from 0-44); higher scores indicate greater frequency and number of overdose risk behaviors.

Secondary Outcome Measures

Name	Time	Method
Number of Steps Achieved Along a Modified SUD Cascade of Care	180 days (6 months)	Number of steps achieved along a modified substance use disorder (SUD) Cascade of Care (0-11 steps possible) at 180 days post-randomization (6 months). Higher scores are associated with better outcomes.

Trial Locations

Locations (3)

Providence Regional Medical Center; 🇺🇸 Everett, Washington, United States

Mercy Health Youngstown; 🇺🇸 Youngstown, Ohio, United States

Prisma Health Upstate; 🇺🇸 Greenville, South Carolina, United States